Albany Physical Activity & Nutrition Project: A home-based physical activity and nutrition program targeting middle-aged adults at risk of metabolic syndrome in a disadvantaged rural community

Not Applicable

• Conditions: Metabolic syndrome; Type 2 diabetes mellitus; Cardiovascular disease; Overweight/obesity; Public Health - Health promotion/education; Diet and Nutrition - Obesity; Metabolic and Endocrine - Metabolic disorders

• Registration Number: ACTRN12614000512628
• Lead Sponsor: WA Centre for Health Promotion Research, Curtin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-05-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 625

Inclusion Criteria

Study participants will be required to be 50-69 years, insufficiently active (less than 150 minutes of moderate physical activity per week), and satisfying the following International Diabetes Federation metabolic syndrome criteria: central obesity (waist circumference greater than 94 cm men or greater than 80 cm women [Europids, Sub-Saharan Africans, Eastern Mediterranean, Middle East]; greater than 90cm men or greater than 80cm women [South Asians, Chinese, Japanese]); plus any two of: raised triglyceride level (greater than 1.7 mM, or treatment for this); reduced HDL-cholesterol (less than 1.03 mM in males and less than 1.29 mM in females, or treatment for this); raised blood pressure (systolic equal to 130 mmHg or diastolic equal to 85 mmHg, or treatment of previously diagnosed hypertension); raised fasting plasma glucose (equal to 5.6 mM). To be at risk of metabolic syndrome, only one instead of two of the above parameters must be satisfied in addition to central obesity.

Exclusion Criteria

The following exclusion criteria will apply: previous diagnosis of diabetes mellitus (other than gestational diabetes); receiving treatment to lower blood glucose; on a weight loss diet or having weight fluctuations of greater than 5% within the past 6 months; involvement in another physical activity program; or a partner/individual residing in the same household as another participant already recruited for the study (to avoid contamination).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Insulin sensitivity (insulin, glucose) - measured by fasting blood samples [6 months post completion of the intervention program];Waist circumference<br>Waist and hip circumference will be measured standing up at the level midway between the lowest rib margin and the iliac crest to the nearest 0.5 cm. Hip circumference will be measured at the largest level of the symphysis pubis and gluteus maximus. Waist-to-hip ratio will be calculated as waist circumference divided by hip circumference.[6 months post completion of the intervention program];Lipid profile (cholesterol, triglycerides) <br>The concentrations of triglycerides, total cholesterol and HDL cholesterol will be measured allowing determination of total-, LDL-, HDL-, and non-HDL-cholesterol levels. All blood tests will be performed by Western Diagnostic Pathology.[6 months post completion of the intervention program]