ChiCTR2000031929已完成4 期
Comparison of efficacy of dermatological 0.1% tacrolimus in treatment on vernal keratoconjunctivitis
No funding1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2019年7月1日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Symptoms
研究概览
简要总结
Tacrolimus has been used in different concentrations for ophthalmic use. It is used in 0.1 % as well as in 0.03% concentrations. Some studies claim it is more effective in 0.1 % concentration. In most studies tacrolimus is studied in bid dose, we intend to check its efficacy in HS dose.
研究设计
- 研究类型
- Interventional
- 主要目的
- 单臂
- 盲法
- N/a
入排标准
- 年龄范围
- 7 至 14（—）
- 性别
- All
入选标准
- •were all the pediatric patients of severe VKC, unmanageable with conventional treatment (anti-histamines/mast cell stabilizers/NSAIDS/steroids) or patients showing recurrence after discontinuation of steroids or having steroid-induced complications.
排除标准
- •were any coexisting ocular disorders such as conjunctival or corneal diseases, ocular infections, uveitis, Stevens Johnson syndrome, contact lens usage, history of ocular surgery. Informed consent was taken and all the patients were explained about the study.
研究组 & 干预措施
Case series
topical application of tacrolimus in conjunctival fornix at night
结局指标
主要结局
Symptoms
Conjunctival Hyperemia
Papillae size
Tranta dots
SPK grade
次要结局
未报告次要终点
研究者
研究点 (1)
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