The effect of tacrolimus eye drop in treatment of herpetic corneal ulcer
Phase 2
- Conditions
- herpetic non-necrotizing stormal keratitis.Herpesviral keratitis and keratoconjunctivitis
- Registration Number
- IRCT2016102429871N2
- Lead Sponsor
- Guilan University of Medical Sciences, Pro-Vice -Chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Cases with non-necrotizing herpetic stromal keratitis that are in active phase of disease.
Exclusion criteria: Cases with necrotizing stromal keratitis or history of corneal graft, History of intraocular operation and trauma, Pregnant and breast feeding women will exclude for this study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in corneal opacity and edema. Timepoint: 3 days, one week, two weeks, three weeks and four weeks after treatment. Method of measurement: clinical exam and scoring.
- Secondary Outcome Measures
Name Time Method Change in corneal vascularization. Timepoint: 3days,one week,two weeks,three weeks and four weeks after treatment. Method of measurement: clinical exam and scoring.