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Evaluation on post treatment pain in patients undergoing Root Canal Treatment with 3 agents Lignocaine,sodium Diclofenac, Ketorolac tromethamine.

Phase 1
Conditions
Health Condition 1: K040- Pulpitis
Registration Number
CTRI/2020/09/027635
Lead Sponsor
Dr Meghna Kothari
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Other (Terminated)
Sex
Not specified
Target Recruitment
198
Inclusion Criteria

1.The patients between 18 to 60 years of age with mandibular teeth where mandibular nerve block is required to anesthetize the tooth.

2.Patients diagnosed with irreversible pulpitis with hot tooth.

3.Patients having history of stage 1 and 2 hypertension and undergoing regular treatment.

4.Patients having no systemic diseases other hypertension would be included.

5.Patient should have actively experiencing moderate to severe pain on VAS scale of 5 or more.

6.Teeth with no well defined periapical radiolucency seen on radiographic examination.

7.Patients with history of previous initiation root canal therapy.

8.A written informed consent will be taken from all the patients and only those patients ready to sign the consent letter

Exclusion Criteria

1. Patients with known hypersensitivity to diclofenac sodium, ketorolac tromethamine and lignocaine.

2. Patients who are pregnant or lactating

3. Patients who are contraindicated for NSAIDs

4. Patients who have undergone cardiac surgery in last 6 months

5. Patients with fractured or visibly cracked tooth, developmental anomalies, pathology or open apex related to study teeth.

6. Patients who had taken NSAIDS within 24 hrs before administration of study drug.

(antibiotic as such no criteria required)

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Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Intraligamentary Injections are known to reduce the pain after giving nerve block in cases of irreversible pulpitis. The generally used agent is lignocaine but other drugs like diclofenac sodium and ketorolac tromethamine are also proved to reduce the intra-appointment painTimepoint: At Baseline and <br/ ><br>Second after getting drop inside the pulp chamber
Secondary Outcome Measures
NameTimeMethod
To evaluate post operative pain following Intraligamentry Injection using lignocaine, diclofenac sodium, ketorolac tromethamineTimepoint: At Baseline <br/ ><br>and <br/ ><br>Second after gaining access to pulp chamber
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