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Clinical Trials/ISRCTN02658871
ISRCTN02658871
Completed
未知

Secondary PREVENTion of schizophrenia: a randomised controlled trial

niversity of Cologne (Germany)0 sites300 target enrollmentDecember 5, 2007
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ConditionsProdromal schizophreniaMental and Behavioural DisordersSchizotypal disorder

Overview

Phase
未知
Intervention
Not specified
Conditions
Prodromal schizophrenia
Sponsor
niversity of Cologne (Germany)
Enrollment
300
Status
Completed
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 5, 2007
End Date
October 31, 2014
Last Updated
7 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Cologne (Germany)

Eligibility Criteria

Inclusion Criteria

  • •Current participant inclusion criteria as of 19/03/2019:
  • •1\. Aged between 18 \- 49 years
  • •2\. Belong to one of the following groups:
  • •2\.1\. Attenuated Positive Symptoms (APS)
  • •2\.2\. Brief Limited Intermittent Psychotic Symptoms (BLIPS)
  • •2\.3\. Predictive basic symptoms
  • •2\.4\. Family risk plus reduced functioning
  • •3\. Verbal Intelligence Quotient (IQ) greater than 70
  • •4\. Written informed consent
  • •Previous participant inclusion criteria:

Exclusion Criteria

  • •1\. Present or past diagnosis of a schizophrenic, schizophreniform, schizoaffective, delusional or bipolar disorder according to Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM IV)
  • •2\. Present or past diagnosis of a brief psychotic disorder according to DSM IV with a duration equal to or of more than one week or within the last 4 weeks regardless of its duration
  • •3\. Diagnosis of delirium, dementia, amnestic or other cognitive disorder, mental retardation, autism spectrum disorders, psychiatric disorders due to a somatic factor or related to psychotropic substances according to DSM IV
  • •4\. Alcohol or drug dependence according to DSM IV
  • •5\. Diseases of the central nervous system (inflammatory, traumatic, epilepsy etc.)
  • •6\. Magnetic Resonance Imaging (MRI) or Electroencephalogram (EEG) abnormalities
  • •7\. Current or past antipsychotic treatment for longer than 1 week
  • •8\. Current or past antipsychotic treatment shorter than 1 week without a washout phase of at least 4 weeks
  • •9\. Current pregnancy, lactation or missing reliable method of contraception
  • •10\. Current suicidality or dangerous behaviour

Outcomes

Primary Outcomes

Not specified

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