The clinical study of alveolar bone tissue engineering for severely atrophic alveolar bone using autologous bone marrow stromal cells
Not Applicable
- Conditions
- severely atrophic alveolar bone
- Registration Number
- JPRN-UMIN000045309
- Lead Sponsor
- Institute of Medical Sciences, University of Toikyo
- Brief Summary
The osteoblastic cells induced from bone marrow were transplanted with autologous platelet rich plasma and b-tricalcium phosphate granules onto severely atrophic maxillary bone. Eight patients were enrolled. Radiographic evaluation and bone biopsies showed bone regeneration in all patients with the average bone area of 41.9%. No side effects were noted. The results showed that bone tissue engineering was safe and feasible.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with diabetes and/or autoimmune diseases,
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method