MedPath

Pulsed Radiofrequency for Emotional Stress

Not Applicable
Completed
Conditions
Chronic Pain
Interventions
Device: Placebo
Device: TcPRF
Registration Number
NCT02972099
Lead Sponsor
Swiss Paraplegic Research, Nottwil
Brief Summary

The objective of the study is to assess the short-term and long-term effects of transcutaneous pulsed radio frequency treatment on the physiological status, subjective well-being, and on the intensity of pain. Category A Transcutaneous Pulsed Radiofrequency is a method that is widely used for control of pain. There are no known complications. In this study a Radiofrequency generator will be used that has a separate outlet for transcutaneous use. Patients will be recruited within the clinic population of patients.

Detailed Description

Data will be assessed in at three times, the baseline testing, the first and the second follow-up meeting (+2-4 days of intervention; as well as + 40 days via post/email)

The inclusion criteria are: Inclusion:

* age 18 - 65

* chronic pain (Duration of three Months or more) patients of the Pain Center Nottwil, Swiss Paraplegic Center

The following criteria will lead to an exclusion of the study:

* severe medical issues, such as cancer or comparable diseases

* severe mental disorders such as severe depression or schizophrenia

* patients with pacemakers or with atrial fibrillation

* Women who are pregnant or breast-feeding The primary outcome assessed is the physiological status, assessed by the heart rate variability (HRV). Secondary outcomes are the subjective well-being, as assessed by the "Marburger questionnaire regarding habitual well-being" (FW-7) questionnaire as well as the intensity of pain, as assessed by the numeric rating scale for pain intensity (NRS) score and by a 7-point Likert scale.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • age 18 - 65
  • chronic pain (Duration of three Months or more) patients of the Pain Center, Swiss Paraplegic Center, Nottwil
Exclusion Criteria
  • severe medical issues, such as cancer or comparable diseases
  • severe mental disorders such as severe depression or schizophrenia
  • patients with pacemakers or with atrial fibrillation
  • Women who are pregnant or breast-feeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Placebo GroupPlaceboThe setup will be made as for active treatment but no current will be delivered. The patients will not be able to feel any difference to the real treatment.
TcPRF GroupTcPRFAccording to the standard application of the device, for the PRF procedure one 5 x 13 cm skin electrode will be placed over the forehead, the other one over the posterior aspect of the neck. PRF with a duty load of 14.8 msec/sec and an average pulse frequency of 5.11 Hz will be applied for 25min. The voltage will be set to generate a current of 1 A. Voltage and impedance will be monitored continuously during treatment and if necessary the voltage will be corrected to ensure the proper current.
Primary Outcome Measures
NameTimeMethod
Physiological status - Change between Baseline and Follow-up 1Baseline; Follow-up 1 (+2-4 days)

physiological status, assessed by the heart rate variability (HRV)

Secondary Outcome Measures
NameTimeMethod
Subjective Wellbeing - Change between Baseline and Follow-up 1 & 2Baseline; Follow-up 1 (+2-4 days); Follow-up 2 (+40 days by post)

Secondary outcome is the subjective well-being, as assessed by the FW-7 questionnaire

Intensity of pain - Change between Baseline and Follow-up 1 & 2Baseline; Follow-up 1 (+2-4 days); Follow-up 2 (+40 days by post)

the intensity of pain is assessed by the Numeric Rating Scale for pain (NRS) score by a 7-point Likert scale

Trial Locations

Locations (1)

Pain Center, Swiss Paraplegic Center

🇨🇭

Nottwil, Luzern, Switzerland

© Copyright 2025. All Rights Reserved by MedPath