The Effect of Transcutaneous Electrical Nerve Stimulation (TENS) in Multiple Sclerosis

Not Applicable

Completed

• Conditions: Multiple Sclerosis
• Interventions: Device: Transcutaneous electrical nerve stimulation

• Registration Number: NCT01280539
• Lead Sponsor: Hasselt University

Brief Summary

In this study the researchers want to investigate the effects of long-term transcutaneous electrical nerve stimulation on the cortical excitability of persons with multiple sclerosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2011-01-19
• Study First Submitted QC: 2011-01-19
• Study First Posted: 2011-01-20
• Primary Completion: 2012-01
• Study Completion: 2012-06
• Status Verified: 2012-09
• Last Update Submitted: 2012-09-04
• Last Update Posted: 2012-09-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Expanded Disability Status Scale (EDSS) scores between 2 and 6.5
• Stable MS (no relapse during the last 3 months before study onset)
• sensory impairment
• age: between 18 and 68 years old

Exclusion Criteria

• Patients with other pathologies associated with peripheral and/or central sensory dysfunction or under psychotropic or antiepileptic medication

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Sham TENS	Transcutaneous electrical nerve stimulation	Sham TENS will be applied to the impaired hand
TENS	Transcutaneous electrical nerve stimulation	Transcutaneous electrical nerve stimulation will be applied on the impaired hand

Primary Outcome Measures

Name	Time	Method
Change in cortical excitability	Baseline, immediately after and 3 weeks after the intervention	Cortical excitability will be assessed using transcranial magnetic stimulation (TMS)

Trial Locations

Locations (1)

Hasselt University (BIOMED); 🇧🇪 Diepenbeek, Limburg, Belgium