跳至主要内容
临床试验/NCT03178903
NCT03178903已完成不适用

tDCS for Increasing Exercise Adherence in Individuals With Elevated Depressive Symptoms

Butler Hospital2 个研究点 分布在 1 个国家目标入组 51 人开始时间: 2017年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
51
试验地点
2
主要终点
Physical Activity Levels

研究概览

简要总结

The purpose of this study is to examine the efficacy of tDCS (transcranial direct current stimulation) for increasing exercise adherence among low active individuals with elevated depressive symptoms. The investigators expect that this project will contribute much needed knowledge about the role that tDCS can play in changing the affective experience of exercise.

详细描述

Exercise adherence is a significant public health problem. Affective experiences during exercise predict long-term physical activity (PA) levels. Therefore, approaches to improving the affective experience of exercise are both important and likely to have high impact. This may be particularly true among individuals with elevated depressive symptoms due to their tendency toward more negative and less positive affect. tDCS is a noninvasive brain stimulation approach with a growing body of literature supporting its effects on cognitive and emotional processing in varied populations, including some support for those with depression. In addition, there is recent increased interest in utilizing tDCS in the context of exercise (see above) and in obesity prevention. While the effects of tDCS on behavioral and cognitive functioning are still developing, promising findings have emerged for tDCS used in repeated combination with a behavioral or cognitive intervention. Given that tDCS is relatively safe, inexpensive, and portable, individuals who struggle with enjoying exercise could be afforded a practical option for increasing and maintaining physical activity levels.

We propose to conduct a pilot randomized controlled trial of tDCS versus sham delivered 3x/week for 8 weeks in the context of a supervised aerobic exercise (AE) program among 72 low-active individuals with elevated depressive symptoms. Follow-up assessments will be conducted at end of treatment, 3, and 6 months.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • be between 18 and 65 years of age
  • be low active
  • have elevated levels of depressive symptoms
  • interested in starting an exercise program in the next month

排除标准

  • history of mania or hypomania
  • current psychotic disorder
  • current DSM-5 diagnosis of an eating disorder
  • DSM-5 moderate and severe substance use disorder
  • current suicidality or homicidality
  • current DSM-5 diagnosis of major depressive disorder that is not currently being treated with pharmacotherapy or psychotherapy
  • physical disabilities or medical problems that would prevent participation in moderate intensity exercise or may be contraindicated for tDCS
  • current pregnancy or intent to become pregnant during the next 8 weeks
  • pacemaker or metal implanted in the cranial cavity

结局指标

主要结局

Physical Activity Levels

时间窗: 8 week assessment

Accelerometry-based moderate-to-vigorous physical activity (MVPA)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验