Evaluation of Retinal Microvascular Change That May Develop in After Open Globe Injury With Optical Coherence Tomography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Anterior Chamber Angle
研究概览
简要总结
The aim of this study is to evaluate posterior segment changes in the non-traumatic eye after open globe injury.
详细描述
Globe injuries can be classified as either closed- or open-globe injuries, based on the integrity of the sclera and cornea. Open-globe injury (OGI) is characterized by a full-thickness wound of the ocular wall.
As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes.
OGI by rupture often occurs at the weakest point of the eye wall, which may or may not be at the actual injury site. The rupture site is most commonly found in the sclera concentric to the limbus, just posterior to the insertion of the extraocular muscles.
After trauma, changes may occur in the non-trauma eye. Retinal and choroidal circulation may change as a result of adaptation mechanisms. In this study, we evaluated the vascular densities of the control group and post-traumatic non-trauma eye.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Be over 18 years old
- •Unilateral eye injury
排除标准
- •Be under the age of 18
- •Usage of systemic drugs or topical ocular drops
- •Bilateral eye injury
- •Having systemic disease, having ocular pathology that may decrease visual acuity
结局指标
主要结局
Anterior Chamber Angle
时间窗: 10 minutes
Anterior chamber angle in degree
Lens Power
时间窗: 10 minutes
in diopters
Anterior Chamber Depth
时间窗: 10 minutes
Anterior chamber depth in mm
Corneal Thickness
时间窗: 10 minutes
Corneal thickness in mikrometer value
Anterior Chamber Volume
时间窗: 10 minutes
Anterior chamber volume in mm3
Steep Keratometry
时间窗: 10 minutes
in Diopters measured with pentacam
Tonometry
时间窗: 10 minutes
Intraocular pressure measurement in mmHg
Axial Length
时间窗: 10 minutes
Axial length in mm
Optic Nerve Head Vessel Density
时间窗: 10 minutes
Optic nerve head vessel density assessed with optical coherence tomography angiography
Choriocapillaris Flow Area
时间窗: 10 minutes
Choriocapillaris flow area assessed with optical coherence tomography angiography
Subfoveal Central Macular Thickness
时间窗: 10 minutes
Subfoveal central macular thickness assessed with optical coherence tomography
次要结局
未报告次要终点
研究者
Aslı Çetinkaya Yaprak
Associate Professor
Akdeniz University