The Effectiveness Of Intravenous Ibuprofen Versus Intravenous Ketorolac For Postoperative Pain Relief After Cesarean Section
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Alexandria University
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- measurement of visual analogue score
Study Overview
Brief Summary
The aim of this study will be to evaluate the effectiveness of intravenous ibuprofen versus intravenous ketorolac for postoperative pain relief after caesarian section
- The Primary outcome is measurement of visual analogue score during rest and movement
- The Secondary outcome is measurement of 24 hours opioids requirements.
Detailed Description
METHODS
- Preoperative assessment:
All parturients included in the study will be assessed thoroughly by:
-
Proper history taking
-
Complete clinical examination.
-
All needed laboratory investigations.
-
Patient preparation:
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Parturients aged 20-30years.
- •ASA physical satatus: II.
- •Anticipated hospital stay for at least 24 hours.
- •Refusal of spinal anaesthesia.
Exclusion Criteria
- •Known allergy to the used drugs.
- •Renal and hepatic impairement
- •History of brochial asthma.
- •Low platelets count (<70000).
- •Bleeding diathesis and with history or risk of intracranial hemorrhage.
- •Obese and morbidly obese parturients.
- •GIT problems as gastritis or GI bleeding.
Arms & Interventions
Group (B):
800mg ibuprofen in 200cc normal saline intravenously every 6 hours for 24hours postoperatively.
Intervention: Ibuprofen 800 mg (Drug)
Outcomes
Primary Outcomes
measurement of visual analogue score
Time Frame: after the surgery average 24 hours postoperative
measurement of visual analogue score during rest and movement . The Score range from 0- 10 . 0 means no pain and 10 indicates the worst pain ever
Secondary Outcomes
- opioids requirements.(after the surgery average 24 hours postoperative)
Investigators
Ahmed Shehab, MD
lecturer Of Anaesthesia and Surgical intensive care
Alexandria University