Long-term Oncologic Outcomes of Minimal Access (Endoscopic or Robotic Assisted) Nipple-sparing Mastectomy Compared With Conventional Approach in Breast Cancer - a Propensity Score Matching Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,129
- 主要终点
- disease free survival
研究概览
简要总结
In this study the investigators investigate the oncological outcomes of minimal access nipple sparing mastectomy compared with conventional nipple sparing mastectomy for the treatment of breast cancer
详细描述
A retrospective analysis of a prospectively collected database was conducted from single institute to compare the oncologic outcomes of MA-NSM versus C-NSM. The clinical results and oncologic outcome (margin involved rate, local recurrence and overall survival) were compared between groups. To prevent bias, a case control approach was conducted with propensity score matching (PSM) method.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •primary operable breast cancer and had undergone NSM
排除标准
- •had metastatic disease, non-malignant breast disease cases, bilateral breast cancer cases, recurrent breast cancer as well as male breast cancer cases and patients who did not undergo NSM
结局指标
主要结局
disease free survival
时间窗: 10 years
disease free survival
overall survival
时间窗: 10 years
overall survival
local recurrence
时间窗: 10 years
local recurrence
distant metastasis
时间窗: 10 years
distant metastasis
次要结局
- operative duration(during surgery)
- intra-operative blood loss(during surgery)
- post-operative complications(30 days post-operatively)