d68Ga-DOTATATE PET/CT Assessment of Cardiac Sarcoidosis
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- 68Ga-DOTATATE Uptake With Cardia Sarcoidosis (CS)
研究概览
简要总结
The Researchers are trying to determine if 68Ga-DOTATATE PET/CT imaging will have a similar accuracy as 18FDG PET/CT in diagnosing cardiac sarcoidosis and if it will be able to do so without the need for complex patient dietary preparation that is required with 18FDG PET/CT.
详细描述
Prospective study of 15 consecutive patients with suspected or newly diagnosed cardiac sarcoidosis (CS) who are referred for a clinically indicated 18FDG (and 13NH3) PET/CT scan for cardiac sarcoidosis (CS) will be approached to undergo a 68Ga-DOTATATE PET/CT scan. Comparison will then be made between the 68Ga-DOTATATE PET/CT and the 18FDG and 13NH3 PET/CT to determine if 68Ga-DOTATATE detects CS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of age or older
- •Referred for clinically indicated 18FDG PET/CT scan for cardiac sarcoidosis (CS)
排除标准
- •Unable or unwilling to give consent for 68Ga-DOTATATE PET/CT scan
研究组 & 干预措施
68Ga-DOTATATE PET/CT
68Ga-DOTATATE PET/CT scan, 18FDG PET/CT scan and 13NH3 PET/CT scan will be performed on each subject
干预措施: 68Ga-DOTATATE PET/CT (Drug)
68Ga-DOTATATE PET/CT
68Ga-DOTATATE PET/CT scan, 18FDG PET/CT scan and 13NH3 PET/CT scan will be performed on each subject
干预措施: 18FDG PET/CT scan (Drug)
68Ga-DOTATATE PET/CT
68Ga-DOTATATE PET/CT scan, 18FDG PET/CT scan and 13NH3 PET/CT scan will be performed on each subject
干预措施: 13NH3 PET/CT scan (Drug)
结局指标
主要结局
68Ga-DOTATATE Uptake With Cardia Sarcoidosis (CS)
时间窗: 3 days
The number of subjects with areas of abnormal myocardial increased focal uptake
18FDG Uptake With Cardia Sarcoidosis (CS)
时间窗: 2 days
The number of subjects with areas of abnormal myocardial increased focal uptake on 18FDG scan
13NH3 PET/CT Uptake With Cardia Sarcoidosis (CS)
时间窗: 2 days
The number of subjects with areas of perfusion deficits on 13NH3 PET/CT scan
次要结局
- Physician Confidence in Study Interpretation(2 days)
- Subject Satisfaction(2 days)
研究者
John P. Bois, M.D.
Assistant Professor of Medicine
Mayo Clinic