Multi Sensory Stimulation And Priming (MuSSAP) in infants (4-12 months of age) at risk of developing Unilateral Cerebral Palsy (UCP).

Completed

Conditions: unilateral Cerebral Palsy/ spasticity
10014623

Registration Number: NL-OMON44918

Lead Sponsor: Sint Maartenskliniek

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 24

Inclusion Criteria

* Born preterm suffering from unilateral periventricular haemorrhagic infarction with involvement of the corticospinal tracts
* Born term suffering from unilateral middle cerebral artery stroke with involvement of the corticospinal tracts
* ±4 months of age (time the infant starts to reach with at least one hand) to 10 months of age (age corrected in case of prematurity)

Exclusion Criteria

* Severe epilepsy
* Severe sensory impairments (blindness, deafness)
* Children with clinical signs of bilateral involvement
* Inability of parents to respond to interviews or questionnaires in Dutch
* Expected inability of parents to adhere to the home-based protocol

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primairy study parameter aims at development of handfunction.<br /><br>At T0, T1 and T2 the following measure will be performed:<br /><br>* Hand Assessment for Infants (HAI)<br /><br>The HAI is currently being developed at the Karolinska Institute of Stockholm<br /><br>(Sweden; Professor Eliasson and Professor Sundholm) in collaboration with the<br /><br>University of Pisa. The HAI is intended to evaluate the quality of<br /><br>goal-directed manual actions in infants, 3-12 months of age, at risk of<br /><br>developing unilateral CP. The test procedure comprises a semi-structured<br /><br>video-recorded 10-15-min play session. HAI is intended to detect and quantify<br /><br>possible asymmetry between hands by providing scores for each hand seperately,<br /><br>and to provide a measure of bilateral hand use (Eliasson et al. 2014). </p><br>

Secondary Outcome Measures