Aloe vera in periodontits

Phase 3

Recruiting

Conditions: Chronic periodontitis is an inflammatory periodontal disease caused by the penetration of germs into the inflamed gums, resulting in periodontal tissue destruction and alveolar bone loss. Chronic periodontitis is the most common form of periodontitis..
Chronic periodontitis
K05.3

Registration Number: IRCT20191113045428N1

Lead Sponsor: Gorgan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 22

Inclusion Criteria

Being over 18 years old
Having at least 20 teeth in the mouth
Having at least one area with probing depth of 4 mm or more in at least two quadrants
Having at least one area of clinical attachment loss of 3 mm or more in at least two quadrants
Necessity to be available during the research process
Having informed consent

Exclusion Criteria

The presence of systemic disease affecting periodontal status
Sensitivity to aloe vera and its products
Receive systemic or topical antibiotic therapy in the past 3 months
Antioxidants intake of vitamin C or E in the past 3 months
Scaling and root planing treatment in the past 6 months
Smoking
Alcohol consumption
Pregnancy and lactation

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Probing Pocket Depth. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Distance of free gingival margin to base of gingival groove by periodontal probe Williams.;Clinical Attachment Loss. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Distance of Cemento Enamel Junction to base of gingival groove by periodontal probe Williams.;Gingival Index. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Specified number to determine the degree: Gingival Index0 (normal), Gingival Index1 (mild), Gingival Index2 (medium), Gingival Index3 (severe).;Plaque Index. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Percentage of adherent microbial plaque on tooth surface: Desirable: 0-30 Average: 31-50 Undesirable: 51-100.

Secondary Outcome Measures