Comparsion the effect of local application of parsley (petroselinium crispum) with hydroquinone cream on reduction the severity of epidermal melasma
- Conditions
- epidermal melasma.Chloasma
- Registration Number
- IRCT2014070518358N1
- Lead Sponsor
- Vice chancellor for research of Gonabad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
Women 50-15 years old (childbearing age); willingness to cooperate in the project; having of epidermal melasma, non-pregnant; Not lactating, not using anti-smudge drugs in the past 30 days , non-contraceptive therapy during the study;No history of epilepsy, liver, thyroid and asthma diseases, no history of allergy to hydroquinone, the lack of any kind of sensitivity to the families Apiaceae plants such as carrots, celery and parsley; not employed in occupations requiring long-term exposure to sunlight (farmers and laborers); Exclusion criteria: pregnancy occurs; sensitivity to hydrocarbons and parsley ; diseases affecting the severity of skin disease and treatment interaction, unwillingness to continue treatment.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Epidermal melasma. Timepoint: before and after intervention. Method of measurement: The melasma severity index and wood lamp.
- Secondary Outcome Measures
Name Time Method