Gastric Ultrasound Assessment for Preoperative Prandial State of Patients Taking Glucagon-Like Peptide-1(GLP-1) Receptor Agonists
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 132
- 试验地点
- 1
- 主要终点
- Number of subjects that are at risk for aspiration
研究概览
简要总结
The purpose of this study is to determine the type of gastric content and quantify the volume of liquid gastric contents using ultrasonography in patients on GLP-1 agonists that have presented for elective surgery and to determine if risk factors are associated with a higher gastric volume in patients on GLP-1 receptor agonists.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients taking GLP-1receptor agonists (N=62)
- •Patients not taking GLP-1 receptor agonists (N=62)
排除标准
- •Previous gastric resection or bypass
- •Gastric band in situ
- •Previous fundoplication
- •Large hiatal hernia
- •Pregnant patients
- •Recent trauma
- •Inability to turn to the right lateral decubitus position
结局指标
主要结局
Number of subjects that are at risk for aspiration
时间窗: end of ultrasound
Risk for aspiration is indicated by the presence of solids, thick fluid, or clear fluids \>1.5ml/kg in the gastric antrum in the right lateral decubitus position
Number of subjects that are at low risk for aspiration
时间窗: end of ultrasound
Low risk for aspiration is indicated by a collapsed gastric antrum or clear fluids \<1.5ml/kg in the gastric antrum in the right lateral decubitus position.
次要结局
- Age(end of ultrasound)
- Number of participants with Gastroesophageal reflux disease (GERD)(end of ultrasound)
- Body mass Index (BMI)(end of ultrasound)
- Physical status as assessed by the American Society of Anesthesiologists (ASA) physical status classification system(end of ultrasound)
- Number of participants with reported nothing by mouth (NPO) status(end of ultrasound)
- Number of participants that have use opioids preoperatively(end of ultrasound)
- Number of participants with diabetes(end of ultrasound)
- Number of participants that are male as indicated in the medical records(end of ultrasound)
- Number of participants that are female as indicated in the medical records(end of ultrasound)
- Pain severity as assessed by the numeric scale(end of ultrasound)
研究者
Sudipta Sen
Assisstant Professor
The University of Texas Health Science Center, Houston