Gastric Ultrasound Assessment for Preoperative Prandial State of Patients Taking Glucagon-Like Peptide-1(GLP-1) Receptor Agonists
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pulmonary Aspiration
- Sponsor
- The University of Texas Health Science Center, Houston
- Enrollment
- 132
- Locations
- 1
- Primary Endpoint
- Number of subjects that are at risk for aspiration
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The purpose of this study is to determine the type of gastric content and quantify the volume of liquid gastric contents using ultrasonography in patients on GLP-1 agonists that have presented for elective surgery and to determine if risk factors are associated with a higher gastric volume in patients on GLP-1 receptor agonists.
Investigators
Sudipta Sen
Assisstant Professor
The University of Texas Health Science Center, Houston
Eligibility Criteria
Inclusion Criteria
- •Patients taking GLP-1receptor agonists (N=62)
- •Patients not taking GLP-1 receptor agonists (N=62)
Exclusion Criteria
- •Previous gastric resection or bypass
- •Gastric band in situ
- •Previous fundoplication
- •Large hiatal hernia
- •Pregnant patients
- •Recent trauma
- •Inability to turn to the right lateral decubitus position
Outcomes
Primary Outcomes
Number of subjects that are at risk for aspiration
Time Frame: end of ultrasound
Risk for aspiration is indicated by the presence of solids, thick fluid, or clear fluids \>1.5ml/kg in the gastric antrum in the right lateral decubitus position
Number of subjects that are at low risk for aspiration
Time Frame: end of ultrasound
Low risk for aspiration is indicated by a collapsed gastric antrum or clear fluids \<1.5ml/kg in the gastric antrum in the right lateral decubitus position.
Secondary Outcomes
- Age(end of ultrasound)
- Number of participants with Gastroesophageal reflux disease (GERD)(end of ultrasound)
- Body mass Index (BMI)(end of ultrasound)
- Physical status as assessed by the American Society of Anesthesiologists (ASA) physical status classification system(end of ultrasound)
- Number of participants with reported nothing by mouth (NPO) status(end of ultrasound)
- Number of participants that have use opioids preoperatively(end of ultrasound)
- Number of participants with diabetes(end of ultrasound)
- Number of participants that are male as indicated in the medical records(end of ultrasound)
- Number of participants that are female as indicated in the medical records(end of ultrasound)
- Pain severity as assessed by the numeric scale(end of ultrasound)