Vaso-inotropic Score and ECMO-VA Support in Post-cardiotomy Cardiogenic Shock.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 2,769
- Locations
- 2
- Primary Endpoint
- Pourcentage of death
Study Overview
Brief Summary
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a well-established lifesaving treatment for refractory cardiogenic shock, with or without concomitant respiratory failure. VA-ECMO is usually started in presence of refractory low cardiac output syndrome following CPB weaning. Currently, there is no consensus about the best timing for implantation and initiation of VA-ECMO in this setting. Some publications have suggested that VIS score could be used to determine the necessity of VA-ECMO in cardiologic area. It was demonstrated that a VIS score between 20 and 40 may be a cut-off value to discuss the implantation of VA-ECMO. Post cardiotomy shock is a very interesting setting because the timing of cardiogenic shock is known and several bias are more controlled than in medical area.
Based on the well-established ability of VIS Score in predicting mortality, we will investigate the role of the VIS Score as a determinant for early VA-ECMO implantation in patients suffering of post-cardiotomy cardiogenic shock.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •age over 18 years
- •Cardiac surgery with cardiopulmonary bypass
- •Post cardiotomy cardiogenic shock
- •ECMO-VA implanted in OR
Exclusion Criteria
- •Heart transplantation
- •Incomplete data in relation to outcomes
- •Cardiac arrest
Outcomes
Primary Outcomes
Pourcentage of death
Time Frame: Day 30
Secondary Outcomes
- 1 - Number of complications(Day 30)
- 3 - number of days in hospital(through study completion, up to 3 months)
- 2 - number of days in intensive care(through study completion, up to 15 days)