Comparison of Connective Tissue Graft (CTG) and Titanium Prepared Platelet-Rich Fibrin (T-PRF) Inserted With a Double Layer Technique on Peri-Implant Soft Tissue Thickening: A Randomized Prospective Clinical Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Peri-implant Mucositis
- Sponsor
- Abant Izzet Baysal University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Peri-implant Soft Tissue Thickness
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The present study aimed to increase the thickness of the gingiva and prevent possible crestal bone resorption by placing the CTG or T-PRF membrane under the mucosa immediately after the implant treatment in individuals with thin gingival phenotype. The null hypothesis was that T-PRF used simultaneously with implant placement can be considered an alternative to CTG.
Detailed Description
Although connective tissue graft (CTG) is considered as the best technique for soft tissue augmentation, limited supply of donor tissue because of palatal vessels and nerves, and postoperative pain may require alternative methods. The purpose of this study is to reduce the crestal bone resorption around the implant site by augmenting the Peri-Implant Soft Tissue with T-PRF (titanium prepared platelet-rich fibrin) or CTG and to compare the effectiveness of the two techniques. Through simultaneous augmentation of the soft tissue by T-PRF or CTG, a total of 30 implants were implanted in 30 patients (12 males, 18 females) with a mean age of 38.4 years. In the test group, implants were placed in thin tissues and thickened with T- PRF membrane at the same time, while in the control group, implants were placed in thin tissues and thickened with CTG at the same time. During the surgery (T 0 ) and at postoperative 3 months (T 1 ), keratinised tissue width (KTW) and Peri-Implant soft tissue thickness (STT) were measured from three points: occlusal part of the alveolar crest (OAC), midbuccal mucosa level (MBML), and over 1 mm of mucogingival junction (MGJ1).
Investigators
Gulbahar
Assistant Professor
Abant Izzet Baysal University
Eligibility Criteria
Inclusion Criteria
- •patients older than 18 years,
- •thin gingiva biotype,
- •one missing tooth in the incisor, canine and premolar area and presence of two natural adjacent teeth
- •no bone increasing procedures prior to and during dental implant,
Exclusion Criteria
- •history of a bleeding disorder or on anticoagulant therapy,
- •immunocompromised state and debilitating disease,
- •smoking and alcoholism,
- •poor oral hygiene,
- •diabetes.
Outcomes
Primary Outcomes
Peri-implant Soft Tissue Thickness
Time Frame: Change from baseline soft tissue thickness at 3 months
The measurement of soft tissue thickness at three points: occlusal part of the alveolar crest (OAC), midbuccal mucosa level (MBML), over 1 mm of mucogingival junction (MGJ1)\]
Secondary Outcomes
- Keratinised Tissue Width (KTW)(Change from baseline keratinised tissue width at 3 months)