NL-OMON34232
Not yet recruiting
Not Applicable
The pathophysiological importance of lower esophageal sphincter distensibility in gastroesophageal reflux disease - LES distensibility in GERD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- heartburn
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 27
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •9 GERD patients with a hiatal hernia
- •9 GERD patients with no hiatal hernia or a hiatal hernia \< 2cm
- •9 healthy volunteers
Exclusion Criteria
- •Surgery of the GI tract other than appendectomy or cholecystectomy
- •Motility disorders of the GI tract leading to delayed gastric emptying or altered intestinal motility
- •Inability to stop the use of medication influencing GI motility for one week
- •Inability to stop the use of proton pump inhibitors for one week
Outcomes
Primary Outcomes
Not specified
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