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Effects of Memory Boot Camp on Brain Function in Adults With Symptoms of Mild Cognitive Impairment (MCI)

Not Applicable
Completed
Conditions
Mild Cognitive Impairment
Interventions
Other: Multi-domain Intervention
Registration Number
NCT04426162
Lead Sponsor
Neurocore
Brief Summary

This is a prospective controlled clinical trial to determine the effects of a 12-week Memory Boot Camp (MBC) program on cognitive function in older adults with symptoms of Mild Cognitive Impairment.

Detailed Description

This prospective trial evaluates the 12-week, multi-domain Memory Boot Camp program for adults ages 55 to 85 with symptoms of mild cognitive impairment. The Memory Boot Camp program incorporates neurofeedback, heart rate variability biofeedback, memory and cognitive training, and one-on-one coaching to encourage behavior change in diet, sleep, physical fitness, and stress reduction. Participants are evaluated via neurocognitive assessments, questionnaires, quantitative electroencephalography parameters, and heart rate variability parameters at four time points: baseline, pre-program, post-program, and follow-up. The trial included a 12-week waiting period between baseline and pre-program, such that each participant acts as their own control, and follow-up takes place six months after completion of the program.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
76
Inclusion Criteria
  • Subjective memory concerns
  • At least a high school education
  • Having a current primary care doctor (or agreement to get a primary care doctor)
  • Ability to read and write English
  • Time availability of 4-5 hours/week
  • Be in good general health
Exclusion Criteria
  • Major depression
  • Known neurological illness (e.g. Alzheimer's or other dementia, Parkinson's, epilepsy, multiple sclerosis)
  • Serious psychiatric diagnosis
  • Substance abuse
  • Complete blindness or deafness
  • Plans to be out of town for more than 10 days during the active phase of the trial
  • Current or past client of the Sponsor
  • Complete blindness or deafness
  • Employee or family member of Sponsor employee

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Memory Boot Camp ParticipantsMulti-domain InterventionAll subjects undergo a 12-week control period, followed by a multi-domain 12-week memory program.
Primary Outcome Measures
NameTimeMethod
Change in Montreal Cognitive Assessment (MoCA)Baseline (Month 0), program start (Month 3), program completion (Month 6), and 6-month post-program follow-up (Month 12).

The MoCA is a validated, brief assessment tool that measures MCI and is widely used. Individuals are scored on seven different domains: visuospatial/executive, naming, attention, language, abstraction, delayed recall, and orientation.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Neurocore Brain Performance Center

🇺🇸

Grandville, Michigan, United States

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