Minimally invasive determination of oxygen extraction ratio in patients undergoing cardiac surgery

Completed

• Conditions: Cardiac surgery; open heart surgery; 10007593

• Registration Number: NL-OMON42604
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 35

Inclusion Criteria

* Elective cardiac surgery
* Older than 18 years
* Presence of a pulmonary artery catheter and central venous line

Exclusion Criteria

* Re-operation
* Aortic valve surgery in cas of severe aortic stenosis
* Bentall surgery
* Arrhythmias (may dampen the signal of pulse oximetry)
* Anemia (Hemoglobin levels of 5.5 mmol/L or lower; decreases oxygen delivery)
* Severe COPD (adaptation of peripheral microvasculature to chronic hypoxia; Gold 3/4)
* Intra-cardiac shunt
* ASA score of 4 and higher and NYHA score exceeding 4

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Invasive and minimal invasive measurements of DO2, VO2 and the oxygen<br /><br>extraction ratio.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>* Cardiac output<br /><br>* Hemoglobin measurements in the laboratory and using a point of care device<br /><br>* SpO2<br /><br>* SaO2<br /><br>* SvO2/ScvO2<br /><br>* O2ER<br /><br>* Lactate</p><br>