Acute effects of a single dose of L-theanine and caffeine combination compared to a placebo on reaction time, and brain activity underlying selective attention in acutely sleep-deprived healthy adults.
- Conditions
- Sleep deprived healthy adults
- Registration Number
- SLCTR/2023/006
- Lead Sponsor
- Faculty of Medicine, University of Peradeniya.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow up complete
- Sex
- Not specified
- Target Recruitment
- Not specified
The participants will be, sleep-deprived healthy young adults between the age of 20-30 years recruited from the community, both male and female.The participants in this study will be acutely sleep-deprived overnight before the day of the testing. The day before testing they will only have a post-lunch siesta for 2 hours. (Further details about sleep deprivation and the test preparation protocol are given in the attached protocol).
All individuals meeting any of the exclusion criteria at baseline will be excluded from study participation
1. Gross impairment of vision or hearing that would prevent the participants from performing neuropsychological tasks
2. Inability to read and follow written instructions
3. The participants who consume more than 5 cups of tea, coffee, or other caffeinated drinks per day.(Assessed by a qualified doctor in a detailed clinical interview conducted with the potential participants).
4. Who have alcohol dependence or abuse (Assessed by a qualified doctor in a detailed clinical interview conducted with the potential participants).
5. Who smoke or consume nicotine in any form. (Assessed by a qualified doctor in a detailed clinical interview conducted with the potential participants).
6. Who use recreational psychoactive drugs
7.Who have any longstanding illnesses like epilepsy, strokes, and any other neurological or psychiatric illnesses and have taken treatment for such illnesses
8. Who have a previous history of head trauma
9. Who have undergone a stressful or traumatic experience in the recent past.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method