Cardiovascular and Muscular Adaptations to Recreational Soccer and Strength Training in Elderly Healthy 65-75-year-old Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- cardiac adaptations
研究概览
简要总结
A one-year intervention study of 41 healthy elderly men aged 65-75-years.Of these, 24 subjects are untrained men with no regular training activity for the last 5 years. After medical screening and pre-testing, they will be randomized into a football group (n=9), a strength-training group (n=9) or a sedentary control group (n=6). Additional 17 subjects are recruited from local football clubs and have been active football players for the last 40 years. Training will be performed 3x1 hour per week and evaluation will take place after 0, 3 and 12 months. Primary endpoints will be changes in cardiac and vascular structure and function measured by advanced echocardiography (tissue Doppler and speckle tracking imaging), and peripheral arterial tonometry (Endo---PAT device). Secondary endpoints will be evaluation of potential changes in VO2 max, blood pressure, muscle capillaries, lipid profile, circulating catecholamines, body composition, and insulin resistance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 75 Years(Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •65-75 year old men
- •non-smoking
- •non-hypertension
- •non- cardiac disease
排除标准
- •cardiac disease
- •biomechanical disorders
- •cardiac medication
结局指标
主要结局
cardiac adaptations
时间窗: after 16 weeks and one year
changes in cardiac function after 16 weeks and one year measured by advanced echocardiography (tissue Doppler and speckle tracking imaging)
次要结局
- Cardiorespiratory fitness, muscular adaptations, Bloodpressure and Glucose tolerance(after 16 weeks and one year)
研究者
Jakob Friis Schmidt
MD PhD student
University of Copenhagen
