Moxibustion for Knee osteoarthritis

Not Applicable

Completed

Conditions: Diseases of the musculo-skeletal system and connective tissue

Registration Number: KCT0000130

Lead Sponsor: Korea Institute of Oriental Medicine

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 212

Inclusion Criteria

1. Diagnosed as idiopathic knee osteoarthritis according to the clinical guideline of American college of Rheumatology
a. Currently have pain at one or both knee
b. Have at least 3 symptoms among the 6 conditions as follows:
1) Aged from 50 to 70 years old
2) Have morning stiffness within 30 minutes
3) Have Crepitus
4) Have Bony tenderness
5) Have Bony enlargement
6) No palpable warmth
2. Have average daily pain over 40 points (0 to 100 point scale)
3. Agreed with written informed consent

Exclusion Criteria

1. Current or past history of inflammatory disease including rheumatoid arthritis
2. Cancer
3. Traumatic injury which might be related to current knee pain
4. Autoimmune disease
5. Significant deformity of knee joints
6. Knee replacement surgery on affected knee
7. Knee arthroscopy within 2 years
8. Steroid injection in knee joints within 3 months
9. Viscosupplement injections in knee joints within 6 months
10. Joint fluid injection within 6 months
11. received acupuncture, moxibustion, cupping or herbal medicine within 4 weeks
12. Uncontrolled hypertension
13. Diabetes mellitus requiring insulin injection
14. life-threatening cardiovascular or neurological events within one year
15. Chronic respiratory disease
16. Hemorrhagic disorder
17. Alcohol or drug addition
18. Active infectious disease including tuberculosis
19. Keloidosis

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Korean Western Ontario and McMaster Universities Questionnaire (K-WOMAC) Global score

Secondary Outcome Measures

Name	Time	Method
K-WOMAC subscale (pain, stiffness, function);The Short-Form 36 Health Survey (SF-36);Beck Depression Inventory (BDI);Physical Performance Test;Patient Global Assessment;Pain Numeric Rating Scale (NRS);C-Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR);Cost-effectiveness analysis;Qualititive study