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ew Smokeless Moxibustion for Knee Osteoarthritis: Study Protocol for A Multicenter, single-Blind, Randomized Controlled Trial

Not Applicable
Conditions
Knee osteoarthritis
Registration Number
ITMCTR2200005754
Lead Sponsor
Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion Criteria
1.Age 40 to 75 years.
2.According to the diagnostic criteria of knee osteoarthritis of American rheumatology society
3.Radiographic confirmation of knee osteoarthritis (Kallgren Lawrence grade = 1)
4.Moderate or more severe knee pain for most of the past month; the subjects visual analog scale baseline score for arthritic pain is 40 points and above.
5.Agree to accept the random assignment, understand and be willing to sign the informed consent form.

Exclusion Criteria

1.Knee pain caused by other diseases such as rheumatoid arthritis, fibromyalgia syndrome, chronic fatigue syndrome and ankylosing spondylitis.
2.Received steroids in the past 3 months.
3.Received acupuncture treatment within 3 months.
4.Hyaluronate was injected into the joints in the past 6 months.
5.History of joint puncture or arthroscopy in the past year.
6.History of the knee/hip replacement surgery or planning to perform such surgery during the trial.
7.Use of other topical treatments, such as topical use of drugs.
8.Presence of any serious diseases including heart disease, lung disease, kidney disease, liver disease or malignant tumor, systemic infection or infectious disease and mental illness.
9.Participation in another clinical study in the past 1 month.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
WOMAC;
Secondary Outcome Measures
NameTimeMethod
VAS;SF-36;
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