Gelofusine® vs Geloplasma® in major abdominal surgery

Not Applicable

• Conditions: Volume expansion during major abdominal surgery; Surgery; Other complications of surgical and medical care, not elsewhere classified

• Registration Number: ISRCTN27267911
• Lead Sponsor: Guy's and St Thomas' NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-07-29
• Study Completion: 2009-05-04
• Last Update Posted: 5 May 2019

Recruitment & Eligibility

• Status: Stopped
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Both males and females
2. 18 years or over
3. Patients undergoing major abdominal surgery in the Enhanced Recovery After Surgery programme at Guy's and St Thomas' NHS Foundation Trust, UK
4. American Society of Anaesthesiologists (ASA) grade 1-3

Exclusion Criteria

1. Known hypersensitivity to Gelofusine® or Geloplasma®
2. Oliguric or anuric renal dysfunction requiring dialysis
3. Estimated glomerular filtration rate (EGFR) <60 ml/min
4. Myocardial infarction within the previous 3 weeks
5. Heart failure (>New York Hearth Association [NYHA] class 2)
6. Liver insufficiency (aspartate aminotransferase >40 U/L, alanine aminotransferase >40 U/L)
7. Absence of written, informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified