ACTRN12615001282572已完成1 期
Effect of induced hypernatremia in patients with ARDS in addition to lung protective ventilation and conservative fluid management therapy, compared to lung protective ventilation and conservative fluid management therapy only, on lung injury score (LIS) and successful extubation
Shailesh Bihari0 个研究点目标入组 40 人开始时间: 2015年11月25日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 16 Years 至 o limit(—)
- 性别
- All
入选标准
- •ICU Patients more than equal to 16 years of age who are i) intubated, ii) within 48 hours of a diagnosis of ARDS (PaO2/FiO2 less than equal to 200 mmHg, PEEP = 5 cm H2O, bilateral opacities on chest Xray and respiratory failure not fully explained by cardiac failure or fluid overload) with a known respiratory risk factor for ARDS.
排除标准
- •Active bronchospasm or a history of significant chronic obstructive airway disease or asthma, moderate and severe traumatic brain injury, the presence of an intracranial pressure monitor, or any medical condition associated with a clinical suspicion of raised intracranial pressure, lack of consent (treating physician or next of kin), inevitable and imminent death, pregnancy,receiving ECMO, invlovement in other prospective clinical studies.
研究者
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