A clinical trial to study the effect of Rifampicin in children with bacterial meningitis
- Conditions
- Health Condition 1: null- Bacterial meningitis
- Registration Number
- CTRI/2015/06/005951
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Patients with clinical features of bacterial meningitis in the form of acute onset of fever ( < 1 week duration) and signs of CNS involvement such as convulsions, lethargy, altered sensorium, neck stiffness.
And
Laboratory criteria (Any one of the following)
o Positive CSF or Latex Agglutination Test (LAT) for H.influenzae, S.pneumoniae, and N.meningitidis
o >10 WBC/ml of CSF, with blood culture positive for any bacteria
o >100 WBC/ml with >50% polymorphonuclear cells and CSF glucose <50% of blood glucose
o >1000 WBC/ml of CSF with >75% polymorphonuclear cells
Patients with features of raised ICP
Previously received antibiotics > 24 hours ,
Developmental delay,
Severe malnutrition
Previously documented immunodeficiency
Infected lumbar puncture site
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method