Rifampin in treatment of acute Idiopathic Central Serous Chorioretinopathy

Phase 2

• Conditions: Idiopathic Central Serous Chorioretinopathy.; Separation of retinal layers

• Registration Number: IRCT2012072810414N1
• Lead Sponsor: Vice Chancellor for research, Guilan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Inclusion criteria :
Cases of Idiopathic Central Serous Chorioretinopathy ( CSCR) with visual symptoms less than one month in one or both eyes; CSCR confirmed by Fluorescien Angiography (F/A) and Optical CoherenceTomography (OCT) including Central Serous Retinal detachment and or Retinal Pigment epithelial detachment without evidence of any other possible case of exudation.
exclusion criteria:
Pregnancy and Lactation; Any Contraindication of Rifampin usage
including liver disorders ; Patients who used Corticosteroid(Oral, injection, oint, spray) in last 6 months; Any clinical or F/A or OCT sign of Chronic or recurrent CSCR; Using drugs which have interaction with rifampin(during study period); Using 5-phosphodiestrase inhibiting drugs in last 6 months.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anatomical Changes. Timepoint: every month till 3 months. Method of measurement: Clinical exam and Optical Coherence Tomography.;Visual Changes. Timepoint: every month till 3 months. Method of measurement: Snelen Chart.

Secondary Outcome Measures

Name	Time	Method
Serum Cortisol Level. Timepoint: every month till 2 months after intervention. Method of measurement: Measuring Serum Cortisol Level at 8 AM.