A randomised controlled trial comparing the Gonadotrophin Releasing Hormone agonist long regimen versus the Gonadotrophin Releasing Hormone agonist short regimen versus the Gonadotrophin Releasing Hormone antagonist regimen in poor responders undergoing in vitro fertilisation treatment
Completed
- Conditions
- Poor ovarian response in In Vitro Fertilisation (IVF)Pregnancy and Childbirth
- Registration Number
- ISRCTN27044628
- Lead Sponsor
- Guy's and St Thomas' NHS Foundation Trust and King' s College London (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 102
Inclusion Criteria
Any woman undergoing an IVF treatment cycle with or without Intra Cytoplasmic Sperm Injection (ICSI) who is considered to be a poor responder is eligible to participate in the trial.
For this study a poor responder is defined as a woman who had a previous IVF treatment cycle in which she was stimulated with a daily dose of Follicle Stimulating Hormone (FSH) of 300 IU or more for at least nine days and:
1. Produced an inadequate number of mature follicles (three or less follicles measuring more than or equal to 17 mm, or
2. Had three or less oocytes retrieved at oocyte retrieval
Exclusion Criteria
1. Women aged more than 40 years
2. Women with a single ovary
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method