A randomised controlled trial comparing the gonadotrophin releasing hormone (GnRH) agonist long regimen versus the GnRH agonist short regimen versus the GnRH antagonist regimen in poor responders undergoing in vitro fertilization treatment. Poor Responders Intervention Trial - PRINT - PRINT

Phase 1

• Conditions: Poor ovarian response in women undergoing In vitro Fertilisation (IVF) treatment.; MedDRA version: 14.1Level: PTClassification code 10056204Term: In vitro fertilisationSystem Organ Class: 10042613 - Surgical and medical procedures

• Registration Number: EUCTR2006-004460-31-GB
• Lead Sponsor: Guy's & St Thomas' NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01-09
• Last Update Posted: 21 August 2017

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Female
• Target Recruitment: 111

Inclusion Criteria

Any woman undergoing an IVF treatment cycle with or without ICSI (Intra Cytoplasmic Sperm Injection) who is considered to be a poor responder is eligible to participate in the trial.

For this study a poor responder is defined as a woman who had a previous IVF treatment cycle in which she was stimulated with a daily dose of FSH of 300IU or more and: -

•produced an inadequate number of mature follicles (three or less follicles measuring >/= 17mm) following stimulation for at least nine days; OR

•had three or less oocytes retrieved at oocyte retrieval.

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years)
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years)
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

•Women aged more than 40 years.

•Women with a single ovary

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified