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Measurement of Urinary Catabolites of PACs as Biomarkers of Consumption of Cranberry Extracts

Phase 1
Completed
Conditions
Urinary Tract Infections
Interventions
Dietary Supplement: Cranberry extract
Registration Number
NCT02087735
Lead Sponsor
Laval University
Brief Summary

The purpose of this cross over pilot study is to investigate the urinary catabolites of Proanthocyanidines (PACs) as biomarkers of cranberry extracts in healthy young women.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
15
Inclusion Criteria
  • Healthy women.
  • 18 to 40 years.
Exclusion Criteria
  • No internet access.
  • No refrigerator access during the 9 hours of sample collection.
  • Women who had or expect to take antibiotic.
  • Women who had or expect to take cranberries, blueberries or bilberries in the form of berries, juice or extracts.
  • Women who had or expect to take dark chocolate.
  • Women who had personal history of acute or chronic renal failure.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
cranberry extract 3.Cranberry extractTwo capsules with a proanthocyanidin standardized cranberry extract of 2 mg.
cranberry extract 2.Cranberry extractTwo capsules with a proanthocyanidin standardized cranberry extract of 36 mg.
cranberry extract 1Cranberry extractOne capsule with a proanthocyanidin standardized cranberry extract of 36 mg and one capsule of placebo cranberry extract.
Primary Outcome Measures
NameTimeMethod
Urinary catabolites of PACswithin 9 hours following the intake of cranberry extracts
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Laval University, Department of Medecine, Institut sur la nutrition et les aliments fonctionnels (INAF).

🇨🇦

Québec, Quebec, Canada

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