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Jiangsu Hengrui Medicine Co., Ltd

🇨🇳China
Ownership
-
Established
1970-01-01
Employees
-
Market Cap
$38.9B
Website
http://www.hrs.com.cn/english/

Clinical Trials

548

Active:37
Completed:252

Trial Phases

5 Phases

Phase 1:297
Phase 2:106
Phase 3:115
+2 more phases

Drug Approvals

5

PHILIPPINES:5

Drug Approvals

Oxaltin

Approval Date
Jul 14, 2025
PHILIPPINES

Caspin

Approval Date
Jul 14, 2025
PHILIPPINES

Cistra

Approval Date
Jul 14, 2025
PHILIPPINES

Irican

Approval Date
Jul 14, 2025
PHILIPPINES

Clinical Trials

Distribution across different clinical trial phases (546 trials with phase data)• Click on a phase to view related trials

Phase 1
297 (54.4%)
Phase 3
115 (21.1%)
Phase 2
106 (19.4%)
Not Applicable
23 (4.2%)
Phase 4
5 (0.9%)

A Trial of SHR-A1811 Compared to Other Antitumor Therapies as Neoadjuvant Treatments in Early-stage or Locally Advanced HER2-positive Breast Cancer

Not Applicable
Not yet recruiting
Conditions
Early-stage or Locally Advanced HER2-positive Breast Cancer
Interventions
Drug: SHR-A1811 for Injection
Drug: Carboplatin for Injection
First Posted Date
2025-09-29
Last Posted Date
2025-09-29
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
650
Registration Number
NCT07196774
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, Shanghai Municipality, China

A Study of HRS-2329 in Participants With Advanced Solid Tumors Harboring RAS Mutations or Amplifications

Not Applicable
Not yet recruiting
Conditions
Advanced Solid Tumors Harboring RAS Mutations or Amplifications
Interventions
Drug: HRS-2329 Tablet
First Posted Date
2025-09-24
Last Posted Date
2025-09-24
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
120
Registration Number
NCT07189949
Locations
🇨🇳

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin Municipality, China

A Pharmacokinetic Study of SHR8554 Injection in the Population With Renal Insufficiency and Healthy Participants

Not Applicable
Completed
Conditions
Moderate to Severe Postoperative Pain
Interventions
First Posted Date
2025-09-24
Last Posted Date
2025-09-24
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
20
Registration Number
NCT07189962
Locations
🇨🇳

The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China

Phase II Clinical Study of SHR2554 Tablets Combined With Other Anti-tumor Treatments in Non-small Cell Lung Cancer Subjects

Not Applicable
Not yet recruiting
Conditions
Locally Advanced or Metastatic Non-small Cell Lung Cancer
Interventions
Drug: SHR2554; SHR-A2102
Drug: SHR2554; Adabelimumab
Drug: SHR2554; SHR-1701
First Posted Date
2025-09-16
Last Posted Date
2025-09-16
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
200
Registration Number
NCT07175220

A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous Bolus and Infusion HRS-9190 in Healthy Adults

Not Applicable
Recruiting
Conditions
Skeletal Muscle Relaxation
Interventions
First Posted Date
2025-08-27
Last Posted Date
2025-09-10
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
40
Registration Number
NCT07142850
Locations
🇨🇳

The Third Xiangya Hospital of Central South University, Changsha, Hunan, China

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News

GIST Treatment Pipeline Shows Robust Activity with 28+ Therapies in Development Across Multiple Clinical Phases

DelveInsight's 2025 pipeline analysis reveals 25+ companies developing 28+ therapies for gastrointestinal stromal tumors, indicating strong industry investment in this rare cancer space.

Hengrui Medicine Advances Cancer Pipeline with Breakthrough Therapy Designations and Clinical Trial Approvals

Jiangsu Hengrui Medicine secured inclusion of two products on China's proposed breakthrough therapy list, highlighting their potential to address unmet medical needs in gastric cancer treatment.

HER2-Positive Gastric Cancer Pipeline Shows Robust Activity with 20+ Companies Developing Novel Therapies

DelveInsight's 2025 pipeline report reveals over 20 companies actively developing more than 20 innovative therapies for HER2-positive gastric cancer treatment.

Tislelizumab Shows Promise as Adjuvant Therapy for High-Risk Hepatocellular Carcinoma Patients

A multicenter retrospective study of 108 patients demonstrated that tislelizumab, with or without tyrosine kinase inhibitors, significantly extended recurrence-free survival in high-risk hepatocellular carcinoma patients after curative resection.

Global Thrombocytopenia Clinical Trials Market Sees Significant Growth in 2025

The global thrombocytopenia clinical trials landscape is expanding rapidly with over 25 pharmaceutical companies developing 25+ treatment therapies, according to recent market analysis.

Hyperuricemia Pipeline Shows Promise with 15+ Emerging Therapies in Development

Global hyperuricemia pipeline comprises 12+ key companies developing 15+ treatment therapies across various clinical stages, according to DelveInsight's 2025 report.

KRAS Inhibitors Market Set to Exceed $2 Billion by 2030 with Next-Generation Therapies Advancing

The global KRAS inhibitors market has experienced over 400% growth since the first approval in 2021, with four drugs now authorized for treating cancers with KRAS mutations.

FDA Rejects Hengrui-HLB Liver Cancer Combination Therapy for Second Time

• The U.S. Food and Drug Administration has issued a second rejection for the liver cancer combination therapy developed by Jiangsu Hengrui Medicine and HLB, dealing a significant setback to their oncology program. • The combination therapy, targeting advanced hepatocellular carcinoma, failed to meet regulatory standards despite previous promising clinical data in Asian populations. • This rejection highlights the ongoing challenges in developing effective treatments for liver cancer, which remains one of the deadliest cancer types with limited therapeutic options.

Robust Clinical Trial Pipeline Fuels Hope for Renal and Breast Cancer Advances

• The renal cancer clinical trial pipeline is robust, with over 70 companies developing more than 75 therapies, including novel immunotherapies and targeted agents. • Breast cancer research is also thriving, with over 100 companies exploring 120+ new drugs, such as antibody-drug conjugates and PARP inhibitors, in clinical trials. • Recent FDA actions, including Fast Track and Breakthrough Therapy designations, highlight the potential of emerging therapies for both renal and breast cancer. • Advances in diagnostics, such as PET imaging agents for clear cell renal cell carcinoma, are also contributing to improved management of these diseases.

Advancements in HER2-Mutant NSCLC Therapies: A Pipeline Overview

Several companies are actively developing novel therapies for HER2-mutant non-small cell lung cancer (NSCLC), indicating a robust pipeline.

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