Reduction of otoacoustic emission with transcranial magnetic stimulation (TMS) of the auditory cortex

• Conditions: click-evoked OAEs; sounds from the ear; 10022396

• Registration Number: NL-OMON32299
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Participated successfully in mentioned MRI studies
Presence of click-evoked OAEs in both ears
No otologic medical history
> 18 years of age

Exclusion Criteria

•Presence of any major medical, neurological or psychiatric diagnoses now or in the past, specific epilepsy, severe head injury, increased intracranial pressure or previous cranial neurosurgery
•Metal parts inside the subject*s head (except in the mouth) or elsewhere in the body
•Cardiac pacemaker and/or implanted medication pump and/or intercardiac lines
•Use of drugs or medications that reduce cortical excitation such as anticonvulsants, benzodiazepines or other sedatives (e.g. antihistamines)
•Use of drugs or medications that reduces the seizure threshold, such as tricyclic anti-depressants and antipsychotic drugs.
•Pregnancy

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The amplitude of the otoacoustic emission of the ear contralateral to the side<br /><br>of the stimulation. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary endpoint will be the difference in amplitude reduction of the<br /><br>OAEs with respect to the different frequencies compared to placebo.</p><br>