Clinical and Procedural Outcomes of Ostial Left Anterior Descending Artery Intervention With or Without Crossover to Left-main
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 72
- 主要终点
- Evaluation of the clinical outcomes using different techniques in ostial LAD
研究概览
简要总结
Prospective interventional study evaluating clinical and procedural outcomes of patients with ostial left anterior descending artery lesion PCI alone or crossover with left main artery
详细描述
Aim of the work:
- Evaluate the clinical and procedural outcomes in patients undergoing percutaneous intervention (PCI) for ostial left anterior descending (LAD) lesions while comparing the outcomes between those treated with a stent crossing over (CO) to the left main (LM) versus ostial stenting (OS) alone.
- Define predictors of success in Ostial LAD lesion PCI.
Patients and methods:
1)Patients:
Inclusion criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with Significant ostial LAD >50% stenosis within 5mm from ostium
- •Either CCS (ongoing symptoms despite medical therapy) or ACS patients.
- •De-novo lesions.
排除标准
- •Those with coronary angiography results such as: (significant disease of the LM more than 40% or ostial LCX greater than 50%).
- •Patients with protected LM.
- •In adherence to a dual antiplatelet regimen by enrolled patients within the first 12 months after the procedure.
结局指标
主要结局
Evaluation of the clinical outcomes using different techniques in ostial LAD
时间窗: 6 months
Evaluate the clinical outcomes in patients undergoing PCI for ostial LAD lesions The primary end points are: -Target vessel related myocardial infarction occuring within 48 hours defined by absolute rise in cardiac troponin (from baseline) ≥35 times upper reference limit plus 1 (or more) of the following criteria: * Flow-limiting angiographic complications. * New "substantial" loss of myocardium on imaging.
次要结局
- Predictors of ostial LAD PCI success(6 months)
- Predictors of PCI success(6 months)
研究者
MA Abdelreheem
Assistant lecturer
Assiut University