Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
Not Applicable
Completed
- Conditions
- PreDiabetes
- Interventions
- Dietary Supplement: Apple cider vinegar
- Registration Number
- NCT05759442
- Lead Sponsor
- Bahria University
- Brief Summary
The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question\[s\] it aims to answer are:
* Efficacy of metformin versus apple cider vinegar in prediabetics
* Safety of metformin versus apple cider vinegar in prediabetics
Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
- Males and Female
- 17-40 years age
- Body Mass index (BMI) overweight and obese
- FBS (100-125 mg/dl)
- HBA1c 5.7% to 6.4%
Exclusion Criteria
- Concomitant medical problems as established diabetes, hepatic or renal insufficiencies etc.
- Known allergy or intolerance to metformin or apple cider vinegar
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Metformin Metformin Hydrochloride (HCL) Tablet Metformin HCl 500 mg per oral twice daily for 12 weeks Apple cider vinegar Apple cider vinegar Apple Cider Vinegar 15ml per day diluted in 200 ml of water for 12 weeks
- Primary Outcome Measures
Name Time Method Glycated Hemoglobin 12 weeks Change in glycosylated hemoglobin (HbA1c ) in percent
Fasting Blood Sugar 12 weeks Change in fasting blood sugar (FBS) in mg/dL
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Diabetologist Clinics (02)
🇵🇰Karachi, Pakistan