“To compare the effect of non surgical periodontal therapy in chronic periodontitis with and without administration of curcumin pastilles-A clinico-microbiological study’’.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- reduction(4mm)in pocket depth
研究概览
简要总结
abstract:-
background:-periodontitis is a infectious disease so the main aim of periodontal therapy is scaling and root planing which is solely not effective so the adjunctive therapy is given such as Medicinal plants have been used as a traditional treatment agent for various human diseases since years.as it is feasible,lesser side effects and ease of availability.so the aim of the study is to compare the the effect of non surgical periodontal therapy in chronic periodontitis with and without administration of curcumin pastilles-A clinico-microbiological study
material and methods :-Thirty chronic periodontitis patients with an age range of 20–50 years with probing pocket depth (PPD) of 4–6 mm were included.A)Test group (15 patients):-Full mouth scaling and root planing was done with ultrasonic instrument with administration of curcumin pastilles. B)Control group(15 patients):-Full mouth scaling and root planning with ultrasonic instrument was done.clinical parameters probing pocket depth,clinical attachment level,plaque index,gingival index,gingival recession were recorded at baseline,after 1 minth and after 3 months and CFU was done.
results;-there were significant reduction in clinical parameters and microbiologic parameters at baseline,after 1 month and after 3 months in test group as compared to control group.
conclusion:-curcumin patilles being an ayurvedic herb is an excellent alternative to other systemic therapeutic agents due to minimal side��’effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Chronic periodontitis with probing pocket depth ≥6mm 2)Presence of atleast 20 teeth.
排除标准
- •Patients with systemic diseases 2)History of periodontal therapy in the past 6 months 3)Patients on antibiotic use within the past 6 months prior to study 4)Allergy to any test materials 5)Pregnant or lactating females 6)Aggressive periodontitis 7)GradeII and gradeIII mobility.
结局指标
主要结局
reduction(4mm)in pocket depth
时间窗: parameters checked at baseline after 1 month and after 3 months
次要结局
- reduction in microbial count after 3 months(parameters assessed at baseline and after 1 and 3 month)