Validation of Energy Expenditure Measurement With Indirect Calorimetry in Pediatric Patients Undergoing Non-invasive Ventilation Through a Single-limb Circuit With Intentional Leak: a Single Center, Cross-over, Non Pharmacological Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Resting energy expenditure (REE)
研究概览
简要总结
Nutritional status in critically ill pediatric patients is considered a fundamental prognostic factor in terms of mortality, morbidity, complications and outcome. Many studies report how predictive equations most commonly applied are inaccurate, therefore under or over estimating the body energy requirements. For this reason, actual measurement of resting energy expenditure (REE) through indirect calorimetry (IC) is considered to be a better approach.
Currently, IC is not validated during the use of non-invasive ventilation.
Aim of the present study is to validate the measurement of REE with IC in pediatric patients undergoing non-invasive ventilation through a single-limb circuit with intentional leak.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 1 Month 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children admitted to the Pediatric Intensive Care Unit who completed the weaning phase from non-invasive ventilation.
- •age ≤ 6 years
- •patients whose parents provided signed informed consent
排除标准
- •age > 6 years
- •patients whose parents didn't provide signed informed consent
结局指标
主要结局
Resting energy expenditure (REE)
时间窗: 1 day
Resting energy expenditure expressed in kcal/kg/die
次要结局
- Respiratory quotient (RQ)(1 day)
- Carbon dioxide production (VCO2)(1 day)
- Oxygen consumption (VO2)(1 day)