The Effect of Applying Modified NUTRIC Scoring System to Evaluate the Nutrition Risk and Giving Different Types of Nutritional Support on Clinical Outcomes in Critically Ill Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- In-hospital mortality
研究概览
简要总结
Malnutrition is very common in critically ill patients. It is quite important to evaluate nutritional status precisely. Heyland et al firstly reported NUTRIC score including age, APACHE II score, SOFA score, number of commorbidities, days from hospital to ICU admission and IL-6. Because the IL-6 is not routinely checked at ICU. A modified NUTRIC score without IL-6 is more practical. Previous studies showed lower in-hospital mortality in higher nutritional risk patients with higher caloric intake compared with lower caloric intake. However, there is still controversial regarding the in-hospital mortality between full caloric feeding and permissive underfeeding in critically ill patients. Herein the investigators conduct a study to investigate what kinds of nutritional supplements will decrease in-hospital mortality in different nutritional risk patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 100 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Medical intensive care unit patients
- •age elder than 20 years old
- •Intubated with ventilator support patients
- •Predicted ICU stay longer than 72 hours
排除标准
- •NPO patients
- •Contraindication for enteral feeding
- •Upper or lower GI bleeding patients
- •Feeding with gastrostomy or Jejunostomy patients
- •Metoclopramide related EPS or Torsades de pointes history
结局指标
主要结局
In-hospital mortality
时间窗: 90 days
mortality or discharge
次要结局
未报告次要终点
研究者
Wang, Chen-Yu
Director of Medical Intensive Care Unit
Taichung Veterans General Hospital
