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Clinical Trials/NCT03365258
NCT03365258
Unknown
Not Applicable

The Effect of Applying Modified NUTRIC Scoring System to Evaluate the Nutrition Risk and Giving Different Types of Nutritional Support on Clinical Outcomes in Critically Ill Patients

Taichung Veterans General Hospital1 site in 1 country150 target enrollmentDecember 28, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Critical Illness
Sponsor
Taichung Veterans General Hospital
Enrollment
150
Locations
1
Primary Endpoint
In-hospital mortality
Last Updated
6 years ago

Overview

Brief Summary

Malnutrition is very common in critically ill patients. It is quite important to evaluate nutritional status precisely. Heyland et al firstly reported NUTRIC score including age, APACHE II score, SOFA score, number of commorbidities, days from hospital to ICU admission and IL-6. Because the IL-6 is not routinely checked at ICU. A modified NUTRIC score without IL-6 is more practical. Previous studies showed lower in-hospital mortality in higher nutritional risk patients with higher caloric intake compared with lower caloric intake. However, there is still controversial regarding the in-hospital mortality between full caloric feeding and permissive underfeeding in critically ill patients. Herein the investigators conduct a study to investigate what kinds of nutritional supplements will decrease in-hospital mortality in different nutritional risk patients.

Registry
clinicaltrials.gov
Start Date
December 28, 2017
End Date
May 31, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Wang, Chen-Yu

Director of Medical Intensive Care Unit

Taichung Veterans General Hospital

Eligibility Criteria

Inclusion Criteria

  • Medical intensive care unit patients
  • age elder than 20 years old
  • Intubated with ventilator support patients
  • Predicted ICU stay longer than 72 hours

Exclusion Criteria

  • NPO patients
  • Contraindication for enteral feeding
  • Upper or lower GI bleeding patients
  • Feeding with gastrostomy or Jejunostomy patients
  • Metoclopramide related EPS or Torsades de pointes history

Outcomes

Primary Outcomes

In-hospital mortality

Time Frame: 90 days

mortality or discharge

Study Sites (1)

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