Minimum effective volume of crystalloid to prevent spinal induced hypotension during elective cesarean delivery: An up-down sequential allocation design.

• Conditions: spinal hypotension; spinal anesthesia; crystalloid; co-load; hypotension; elective cesarean delivery

• Registration Number: TCTR20200213001
• Lead Sponsor: Department of Anesthesiology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-13
• Study Completion: 2021-09-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Singleton term pregnancy
Elective cesarean delivery
American Society of Anesthesiology classification I-II

Exclusion Criteria

Pregnant woman who has hypertensive disorder
Cardiac pathologies/ Fluid overload and contraindicated for fluid loading
Pregnant woman with extreme height (< 150 cm, > 190 cm)
BMI > 35 kg/m2 at the time of delivery
Patient who has inadequate spinal anesthesia or high spinal/ total spinal anesthesia
Refusal to participate the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Volume of crystalloid fluid At the end of operation Measuring by infusion pump

Secondary Outcome Measures

Name	Time	Method
Hemodynamic parameters At the start of operation,2.5,5,7.5,10,12.5,15,17.5,20 mins after start operation Non invasive cardiac output monitoring