Interactive Stepping Exercise on Balance and Cognitive Function

Not Applicable

• Conditions: Parkinson's Disease

• Registration Number: NCT04494906
• Lead Sponsor: National Yang Ming Chiao Tung University

Brief Summary

The objective of this study is to investigate the effects of interactive stepping exercise on balance and cognitive function in individuals with PD.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-07-28
• Study First Submitted QC: 2020-07-28
• Study First Posted: 2020-07-31
• Status Verified: 2020-08
• Study Start: 2020-08-19
• Last Update Submitted: 2020-08-25
• Last Update Posted: 2020-08-27
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Idiopathic PD
• Hoehn & Yahr stage between 1 to 3
• Age between 50 to 85
• Stable pharmacologic treatment for the last 2 weeks
• Ability to walk 10 meters unassisted or with assistive devices

Exclusion Criteria

• Other neurological disorders diagnosis than PD
• Receiving any neurological surgeries
• Any musculoskeletal disorder or cardiopulmonary disease that may influence participation in the study
• The Mini-Mental State Examination (MMSE) < 24 scores
• Participated in other exercise intervention of study in the past 3 months
• Colorblindness or color vision deficiency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
One-leg stance test	Change from baseline at 8 weeks and 12 weeks	To evaluate static balance ability
Timed up and go test	Change from baseline at 8 weeks and 12 weeks	To evaluate functional walking ability
Digit span test	Change from baseline at 8 weeks and 12 weeks	To evaluate executive function
Sharpened Romberg test	Change from baseline at 8 weeks and 12 weeks	To evaluate static balance ability
Stroop color and word test Chinese version	Change from baseline at 8 weeks and 12 weeks	To evaluate executive function
Trail-making test Chinese version	Change from baseline at 8 weeks and 12 weeks	To evaluate executive function
Spatial span test	Change from baseline at 8 weeks and 12 weeks	To evaluate visuospatial ability
Mini-Balance Evaluation Systems Test	Change from baseline at 8 weeks and 12 weeks	To evaluate balance ability
Montreal Cognitive Assessment Chinese version	Change from baseline at 8 weeks and 12 weeks	To evaluate global cognitive function
Romberg test	Change from baseline at 8 weeks and 12 weeks	To evaluate static balance ability

Secondary Outcome Measures

Name	Time	Method
10-meter walk test	Change from baseline at 8 weeks and 12 weeks	To evaluate walking ability
Parkinson's Disease Questionnaire 39	Change from baseline at 8 weeks and 12 weeks	To evaluate the quality of life

Trial Locations

Locations (1)

National Yang-Ming University; 🇨🇳 Taipei, Taiwan