A study to compare the effect of low dose versus conventional dose intrathecal fentanyl with hyperbaric bupivacaine on the block characteristics in parturient undergoing caesarean section under spinal anaesthesia
Not Applicable
- Conditions
- Health Condition 1: O82- Encounter for cesarean delivery without indication
- Registration Number
- CTRI/2021/08/035932
- Lead Sponsor
- airikyengbam Sheityajit Roy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
(ASA) physical status I or II undergoing lower segment caesarean section under spinal anaesthesia
Exclusion Criteria
1.History of allergy to study drugs
2.Bleeding disorder-platelet count
<50,000/micro litre, prothrombin
time >14sec,International normalised
ratio(INR)- >1.5
3.Local site infection
4.Cardiac, respiratory diseases and
kidney disorder, neurological deficit
5.Spinal deformity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of analgesia [Time (minutes) to demand of first rescue analgesic assessed by visual analogue scale]Timepoint: From time of intrathecal injection (baseline) to the time when patient first demands rescue analgesia (minutes)
- Secondary Outcome Measures
Name Time Method 1.Hemodynamic profile- pulse rate, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), Oxygen saturation (SpO2) <br/ ><br>2.Time of sensory block at onset T 10(secs) <br/ ><br>3.Maximum sensory level achieved <br/ ><br>4.Time to achieve maximum sensory level(secs) <br/ ><br>5.Time to complete motor blockade(secs) <br/ ><br>6.Time to two segment regression(mins) <br/ ><br>7.Time to sensory regression to S2(mins) <br/ ><br>8.Side effects <br/ ><br>Timepoint: 1. Hemodynamic profiles will be assessed at baseline, every 2 minutes till 10 minutes and then every 5 mins till the end of surgery. <br/ ><br>2. The various time intervals will be assessed just after the intrathecal injection and then every 2 mins along the mid -clavicular line, bilaterally till the desired effect/ regression were achieved(sec/mins). The maximum sensory level achieved was also assessed in the mid -clavicular line bilaterally.