Efficacy of oral low-dose Isotretinoin in the treatment of acne vulgaris
Phase 2
- Conditions
- Acne vulgaris.Acne vulgaris
- Registration Number
- IRCT2015061722780N1
- Lead Sponsor
- Vice chancellor for research of Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Absence of hypersensitivity to Retinoid; Absence of pregnancy or plan of pregnancy; no history of hormonal abnormality
exclusion criteria: impossible to follow up; use of another treatment
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quantity of skin lesions of acne vulgaris. Timepoint: At first and six months after initiation of treatment and six months after cessation of treatment. Method of measurement: Computation of lesions and utilization of global acne grading system.
- Secondary Outcome Measures
Name Time Method Increase of liver enzymes and increase of serum lipid profile. Timepoint: At first and one and two and four and six months after initiation of treatment. Method of measurement: Transmission of blood sample to medical laboratory.