Spinal Motor Evoked Potentials in Brain Surgery
- Conditions
- GliomaBrain Tumor
- Registration Number
- NCT02402075
- Lead Sponsor
- Heinrich-Heine University, Duesseldorf
- Brief Summary
During neurosurgical resection of brain tumors within brain areas for motor control, it is important to monitor motor function. For this muscle motor evoked potentials are used. Those are elicited by transcranial and direct cortical stimulation. Motor responses are recorded from muscles. In neurosurgical procedures for spinal cord tumors, the same methods are used, but additionally motor activity is recorded from the spinal cord. This is called spinal motor evoked potentials. It is known that the relation between spinal and muscle motor evoked potentials helps to extent the resection of spinal cord tumors. This study implements the spinal motor evoked potential into brain tumor surgery and analyses the relationship between spinal and muscle motor evoked potentials. With this, detection of injury to the brain area for motor control might be discovered earlier and thus tumor resection can be performed safely.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
- > 18 years
- tumor location adjacent to the motor cortex and corticospinal tract
- minor
- neurological degenerative diseases
- neurological immunological diseases
- drug abuse
- implanted medical devices such as cardiac pacemaker
- spine deformation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical motor status according to the MRC scheme 6 months clinical motor status according to the MRC scheme
D-wave measurement 24 hours numeric assessment, amplitude and latency of D-wave
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Neurosurgical Department
🇩🇪Duesseldorf, Germany
Department of Neurosurgery
🇩🇪Frankfurt, Germany