Comparison of Continuous Moderate-Intensity Training and High-Intensity Interval Training on Vasodilators And Cardiac Function in Type 2 Diabetes

Not Applicable

• Conditions: Type 2 diabetes.; Type 2 diabetes mellitus

• Registration Number: IRCT20181219042056N1
• Lead Sponsor: Vice president of of Research of Tehran University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 May 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

Age 45 to 60 years.
According to Defined by American Diabetes Association 2015, fasting blood sugar (FBS) more than 7 mmol/L.
Glycosylated Haemoglobin (HbA1c) above 6%.
Type 2 Diabetes.
Pre- or stage I hypertension, or treated hypertension (systolic blood pressure 120–159 mmHg, diastolic blood pressure 80–99 mmHg).
Patients with history of Type 2 Diabetes for at least 2 years.
No exercise training in the previous 6 months.

Exclusion Criteria

Patients with FBS more than 22 mmol/L.
HbA1c above 10%.
Myocardial infarction, coronary artery bypass surgery or angioplasty, chronic heart failure, cardiac arrhythmia, functional limitations (such as osteoarthritis), liver or kidney disease, and smoking.
Hypertension, or treated hypertension (systolic blood pressure 170 mmHg, diastolic blood pressure 100 mmHg).

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Adropin Factor. Timepoint: Before and After from 12 week exercise. Method of measurement: Using the Laboratory Elisa Kit.;Nitrite/Nitrate plasma. Timepoint: Before and After from 12 week exercise. Method of measurement: Using the Laboratory Elisa Kit.;HOMA-IR. Timepoint: Before and After from 12 week exercise. Method of measurement: HOMA-IR.;Glucose. Timepoint: Before and After from 12 week exercise. Method of measurement: Enzymatic.;Peak consumption oxygen. Timepoint: Before and After from 12 week exercise. Method of measurement: Gas analyser system.;Diastolic and systolic blood pressure. Timepoint: Before and After from 12 week exercise. Method of measurement: oscillometric device.;Heart rate rest. Timepoint: Before and After from 12 week exercise. Method of measurement: Cornometer/ numbere.;Insulin. Timepoint: Before and After from 12 week exercise. Method of measurement: ELISA kit.