Recovery of mobility after stroke

Not Applicable

Completed

• Conditions: Ischemic stroke (first event); Circulatory System; Ischemic stroke, cerebral infarction

• Registration Number: ISRCTN85999967
• Lead Sponsor: niversity of Basel

Brief Summary

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32938425/ protocol (added 21/09/2020) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37140729/ results (added 09/05/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-08-13
• Study Completion: 2022-02-08
• Last Update Posted: 22 May 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

1. First ischemic stroke within the past 3 months
2. Aged =18 years
3. Able to communicate verbally with the study personnel
4. Able to understand the study information and to provide written informed consent
5. At least one of the following stroke-related symptoms potentially affecting gait/mobility must be present:
5.1. Lower limb paresis or ataxia
5.2. Stance/gait ataxia (cerebellar or sensory)
5.3. Visual disturbance/field defect
5.4. Central vestibular deficit
5.5. Attentional deficit/neglect
6. Able to get up from a chair and sit down without external help
7. Able to walk for a minimum of 20 m at own pace, with or without pauses, with or without a walking aid, but without the physical assistance of another person (self-report)

Exclusion Criteria

1. Not community-dwelling
2. Unable to walk without assistance, wheelchair-bound, or permanently bedridden (modified Rankin Scale, mRS >3 points)
3. Presence of severe cognitive impairment (Montreal Cognitive Assessment (MoCA) score <21 or, <20 for persons with 12 years of education or less)
4. Acute psychiatric disorder (e.g. severe depression)
5. Advanced terminal illness
6. Orthopaedic surgery of the lower extremities within the past year
7. On-going rehabilitation measures following an inpatient surgical procedure at the time of stroke
8. Major pre-stroke mobility limitations (major difficulties in walking or climbing stairs; self-report)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Walking ability and perceived mobility limitation assessed by self-report at 3, 6, 9, and 12 months after stroke2. Lower extremity physical function measured using a battery of tests including quantitative gait analysis, tests of lower limb muscle power, balance tests and functional tests in a given order at the study centre assessed at 3, 6, 9, and 12 months after stroke3. Life-space measured using GPS and by self-report questionnaire at 3, 6, 9, and 12 months after stroke4. Reasons for going outdoors, transportation use, and need for assistance measured using a questionnaire tool that is based on digital maps at 3, 6, 9, and 12 months after stroke

Secondary Outcome Measures

Name	Time	Method
There are no secondary outcome measures