Promoting Activity, Independence and Stability in Early Dementia and Mild Cognitive Impairment 2

Not Applicable

Completed

Conditions: Dementia, mild cognitive impairment
Mental and Behavioural Disorders

Registration Number: ISRCTN15320670

Lead Sponsor: ottingham University Hospitals NHS Trust

Brief Summary: 2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31888709 protocol (added 02/01/2020) 2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32859666/ protocol (added 02/09/2020) 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/35858870/ results of the sub-set of the PrAISED study participants receiving the intervention during during a lockdown in response to the COVID-19 pandemic (added 21/07/2022) 2022 Preprint results in https://doi.org/10.1101/2022.12.20.22283699 Primary and secondary results (added 03/01/2023) 2023 Preprint results in https://doi.org/10.1101/2023.03.26.23287750 Commissioner and stakeholder perspectives (added 31/03/2023) 2023 Results article in https://doi.org/10.1136/bmj-2023-074787 (added 30/08/2023) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37603841/ (added 06/12/2023) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38650466/ (added 24/04/2024)

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 730

Inclusion Criteria

1. Age 65 years or over (no maximum)
2. Diagnosis of MCI or dementia (of any subtype, except Dementia with Lewy Bodies i.e. Parkinson's Disease Dementia)
3. Have a carer or friend who knows the participant well (at least one hour a week contact over the phone, internet, or in person), and is willing and able to act as an informant
4. Able to walk without human help
5. Able to communicate in English
6. Able to see, hear and have dexterity sufficiently to perform neuropsychological tests
7. Have capacity to give consent to participate, and consenting to do so

Exclusion Criteria

1. Co-morbidity preventing participation (e.g. severe breathlessness, pain, psychosis, Parkinson’s or other severe neurological disease)
2. Life expectancy of less than one year
3. Likely to be unable to undertake the intervention regularly (e.g. planned elective surgery, planning to move away or commitments elsewhere).