Efficacy of Pectoral Nerve Block for Breast Reduction Surgery

Completed

• Conditions: Nerve Blocks; Postoperative Pain; Breast Surgery
• Interventions: Procedure: PECS group; Procedure: Control group

• Registration Number: NCT03857386
• Lead Sponsor: Antalya Training and Research Hospital

Brief Summary

The purpose of the study is to evaluate the efficacy of PECS block applied to patients undergoing bilateral breast reduction surgery on postoperative analgesia compared to local infiltration anesthesia.

Detailed Description

Pectoral nerve block (PECS block) has been developed as an alternative to thoracic paravertebral and/or thoracic epidural blocks in recent years. It is frequently applied for postoperative analgesia especially in breast cancer surgery and subpectoral breast prosthesis.

Study Timeline

• Study Start: 2017-07-01
• Primary Completion: 2018-03-01
• Study Completion: 2018-05-01
• Study First Submitted: 2018-12-18
• Study First Submitted QC: 2019-02-26
• Study First Posted: 2019-02-28
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-26
• Last Update Posted: 2019-04-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 53

Inclusion Criteria

• American Society of Anesthesiology (ASA) I-II
• body mass index (BMI) ≤40 kg/m2
• elective bilateral breast reduction surgery

Exclusion Criteria

• declining to give written informed consent
• ASA III and above
• under 18 years of age or over 65 years of age
• history of allergy against to the local anesthetics,
• controendication of peripheral block or local anesthetic infiltration (local infection, coagulopathy, etc.)
• history of breast surgery
• treatment due to psychiatric disorder
• history of treatment for a chronic pain
• history of nerve blocks in order to treat postoperative pain

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
PECS group	PECS group	Preoperative bilateral PECS I + PECS II Pecs block performed by anaesthetist using ultrasound guidance in plane approach
Control group	Control group	Bilateral local anesthesia infiltration Local infiltration anesthesia performed by surgeon during the operation

Primary Outcome Measures

Name	Time	Method
postoperative visual analog scale (VAS) score	postoperative 0, 1, 3, 6, 9, and 12 hours	Postoperative pain assessment will be performed using the VAS score (VAS 0 = no pain, VAS 10 = most severe pain possible). The VAS scores will be recorded at postoperative 0, 1, 3, 6, 9, and 12 hours.

Secondary Outcome Measures

Name	Time	Method
analgesia consumption	during the surgery	intraoperative
length of hospital	4 days	recorded at the following time after surgery

Trial Locations

Locations (1)

Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation; 🇹🇷 Antalya, Turkey