Continuous Pectoral Nerve Block in Breast Cancer Surgery

Not Applicable

Completed

• Conditions: Nerve Blocks; Breast Surgery; Postoperative Pain
• Interventions: Procedure: PECS group; Other: Control group

• Registration Number: NCT04036370
• Lead Sponsor: Antalya Training and Research Hospital

Brief Summary

The purpose of the study is to evaluate the effect of continuous pectoral nerve block on postoperative analgesia consumption in breast cancer surgery.

Detailed Description

Pectoral nerve block has been developed as an alternative to thoracic paravertebral and/or thoracic epidural blocks in recent years. It is frequently applied for postoperative analgesia in breast cancer surgery.

Study Timeline

• Status Verified: 2019-07
• Study First Submitted: 2019-07-25
• Study First Submitted QC: 2019-07-25
• Study First Posted: 2019-07-29
• Study Start: 2019-07-30
• Primary Completion: 2019-11-15
• Study Completion: 2019-11-15
• Last Update Submitted: 2019-11-15
• Last Update Posted: 2019-11-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 48

Inclusion Criteria

• American Society of Anesthesiology (ASA) I-II
• 18-65 years
• Body mass index (BMI) ≤40 kg/m2
• Elective breast cancer surgery

Exclusion Criteria

• ASA ≥4
• under 18 years of age or over 65 years of age
• declining to give written informed consent
• history of allergy to the local anesthetics
• contraendications of peripheral block or local anesthetic infiltration (local infection, coagulopathy, etc)
• history of breast surgery
• treatment due to psychiatric disorder
• history of treatment for chronic pain
• history of nerve blocks in order to treat postoperative pain

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PECS group	PECS group	In addition to routine analgesic protocol; before anaesthesia induction; following the PECS I + II block, a continuous infusion catheter will be placed at the PECS II block level under the guidance of USG, and local anesthetic infusion will be started via the catheter at the end of the operation.
Control group	Control group	Peroperative and postoperative routine analgesic protocol will be performed with no additional intervention (block).

Primary Outcome Measures

Name	Time	Method
analgesia consumption	12 hours	postoperative 12 hours

Secondary Outcome Measures

Name	Time	Method
analgesia consumption	during the surgery	intraoperative
postoperative Numeric Rating Scale (NRS) score	0, 1, 3, 6, 9, 12 hours	postoperative pain assessment will be performed using NRS score (NRS 0=no pain, NRS 10= most severe possible). The NRS scores will be recorded at postoperative 0, 1, 3, 6, 9, 12 hours

Trial Locations

Locations (1)

Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation; 🇹🇷 Antalya, Turkey